Your participation is helping researchers learn about the long-term effects of the medications on reducing heart attack and stroke in people with type 2 diabetes. We truly appreciate your time and commitment to help advance care for people with type 2 diabetes.

Who is eligible to participate in PRECIDENTD?

People with type 2 diabetes who are either:


If these are true for you, click below to contact us!

What does the study involve?

All study medications are approved by the FDA to treat type 2 diabetes.

A computer will randomly assign you to take:

• An SGLT2 inhibitor such as JardianceFarxigaInvokana

• A GLP-1 receptor agonist such as VictozaTrulicityOzempicRybelsus

All participants will be randomized to an active drug. This study does not include a placebo group/arm.

How long does the study take?

This study lasts through 2029 because we want to see what the long-term effects of the medications are on important outcomes like heart attack and stroke.

Our study team will work with your regular health care provider to fit the study medication into your usual diabetes care. Your current diabetes medications may be adjusted.

What are the costs?

Medications and lab tests will be billed to your insurance company. Our study team will help assess your insurance coverage.

What are the rewards?

These medications can lower blood sugar, lower A1C, help with weight loss and prevent heart problems.

You will be paid $500 for each year that you take part in the study.

Where can I participate?

Participating Study Locations. For contact information on each site, please visit the Study Locations page.

Columbia University

Duke University

Essentia Health

Johns Hopkins University

University of Missouri

Medical University of South Carolina

Vanderbilt University

Medical College of Wisconsin